← Related articles Carpal Tunnel Syndrome: Causes, Symptoms, Diagnosis, and Treatment

Carpal Tunnel Syndrome: Causes, Symptoms, Diagnosis, and Treatment

Updated: August 1, 2026
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Carpal tunnel syndrome (CTS) is one of the most common nerve compression disorders, occurring when the median nerve — which runs through the wrist's carpal tunnel — is compressed. It affects people who perform repetitive hand and wrist movements, and is more common in certain occupations, during pregnancy, and in people with conditions such as diabetes, thyroid disorders, or arthritis.

Symptoms

Causes and risk factors

The carpal tunnel is a narrow passageway of bone and ligament at the base of the hand. Anything that narrows this tunnel or enlarges the tissues within it can compress the median nerve: repetitive hand/wrist movements, prolonged wrist positions (flexion or extension), wrist injuries, pregnancy-related fluid retention, obesity, diabetes, and inflammatory conditions.

Diagnosis

Diagnosis is based on symptoms and a physical exam (including Tinel's sign and Phalen's test), and can be confirmed with nerve conduction studies (electromyography/nerve conduction velocity) that measure how well the median nerve conducts signals. Ultrasound can also visualize the nerve and tunnel.

Treatment

Early recognition and treatment improve outcomes — prolonged compression can lead to permanent nerve damage and muscle wasting at the base of the thumb. This article is for general educational purposes and is not a substitute for individualized medical advice; see a doctor for proper diagnosis.

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Source: National Institute of Neurological Disorders and Stroke (NINDS)